Cas No. |
Product name |
192441-08-0 |
Lomeguatrib |
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Lomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM. |
1020149-73-8 |
SGI-1027 |
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SGI-1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively. |
1138549-36-6 |
CX5461 |
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CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fol... |
1346574-57-9 |
GSK126 |
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GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase with Ki value of 0.5 nM. |
503468-95-9 |
NU-7441 |
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NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM. |
1392399-03-9 |
BIX01294 |
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BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM. |
1202055-34-2 |
NMS-P715 |
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NMS-P715 analog is the analog of NMS-P715, which is the first selective, ATP-competitive and orally bioavailable MPS1 small-molecule inhibitor(IC50=8 nM); selectively reduces... |
1044870-39-4 |
RVX-208 |
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RVX-208(RVX 000222) is a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo; is a BET bromodomain antagonist. |
529488-28-6 |
Genz-644282 |
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Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity(IC50=1.2 nM). |
48208-26-0 |
RG108 |
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RG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM, does not cause trapping of covalent enzymes. |